Taysha Gene Therapies prices $200M public offering of common stock
Taysha Gene Therapies, Inc. announced the pricing of a public offering comprising 32,500,001 shares of common stock at $6.00 per share and pre-funded warrants for 833,333 shares at $5.999 each, targeting gross proceeds of approximately $200.0 million. The offering is scheduled to close on June 26, 2026, with underwriters granted a 30-day option to purchase additional shares. Jefferies, Goldman Sachs & Co. LLC, Piper Sandler, and Cantor are acting as joint book-running managers, while Baird serves as lead manager.

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Taysha Gene Therapies, Inc. has priced an underwritten public offering of 32,500,001 shares of its common stock at a price to the public of $6.00 per share. The company also offered pre-funded warrants to purchase 833,333 shares of its common stock at an offering price of $5.999 per pre-funded warrant. The gross proceeds from the offering are expected to be approximately $200.0 million, before deducting underwriting discounts and commissions and other offering expenses. The offering is expected to close on or about June 26, 2026, subject to customary closing conditions.
All securities are being offered by Taysha, which has granted the underwriters a 30-day option to purchase up to an additional 5,000,000 shares of common stock at the public offering price, less underwriting discounts and commissions. A shelf registration statement was filed with the Securities and Exchange Commission (SEC) on November 4, 2025, and became automatically effective upon filing. The offering is being made only by means of a written prospectus and prospectus supplement.
Jefferies, Goldman Sachs & Co. LLC, Piper Sandler, and Cantor are acting as joint book-running managers for the proposed offering. Baird is serving as the lead manager. Taysha is a clinical-stage biotechnology company focused on advancing adeno-associated virus (AAV)-based gene therapies for severe monogenic diseases of the central nervous system.
Taysha’s lead clinical program, TSHA-102, is in development for Rett syndrome, a rare neurodevelopmental disorder with no approved disease-modifying therapies. The company leverages its manufacturing process and a clinically and commercially proven AAV9 capsid to translate treatments from bench to bedside.
| Role | Firm |
|---|---|
| Joint Book-Running Manager | Jefferies |
| Joint Book-Running Manager | Goldman Sachs & Co. LLC |
| Joint Book-Running Manager | Piper Sandler |
| Joint Book-Running Manager | Cantor |
| Lead Manager | Baird |
How will the $200 million in gross proceeds be allocated across Taysha’s clinical programs, particularly TSHA-102 for Rett syndrome?
What are the upcoming clinical milestones for TSHA-102 that investors should monitor following this capital raise?
How might the dilution from the share offering impact shareholder value and investor sentiment in the short term?













