Medifast launches Trilivy metabolic health system with new science
Medifast launched Trilivy, a comprehensive metabolic health system featuring the Trilivy Reset Fueling line enhanced with MetaVantage Technology. The system targets metabolic dysfunction through Metabolic Synchronization across three phases, aiming to reduce visceral fat and retain lean mass. Newly formulated meal replacements are planned to debut in August.

*this image is generated using AI for illustrative purposes only.
Medifast, Inc. has launched Trilivy, a comprehensive metabolic health system designed to support healthy lifestyle changes through science and human connection. The new system introduces the Trilivy Reset Fueling line enhanced with MetaVantage Technology, a platform of proprietary ingredient formulas intended to optimize metabolism by unlocking key metabolic pathways. This launch marks a corporate transformation from the OPTAVIA brand to a focus on optimal metabolic health, addressing challenges impacting more than 90% of U.S. adults.
The transition to Trilivy represents an evolution of the company’s vision, expanding beyond traditional weight loss to broader metabolic health. "Trilivy honors the strong foundation we've built while embracing a brand that reflects where we're headed: a modern metabolic health company built for today’s world and tomorrow’s opportunities," said Nick Johnson, CEO of Medifast. The system integrates breakthrough science, individualized support, and sustainable habit creation to help people transform their metabolic health.
At the center of the system is Metabolic Synchronization, the company’s breakthrough science that targets metabolic dysfunction through three key mechanisms. The system is structured across three phases: Reset to reverse metabolic dysfunction, Refine to improve metabolic flexibility, and Renew to optimize metabolic health and support healthspan.
Metabolic Synchronization Mechanisms
| Mechanism | Function | Outcome |
|---|---|---|
| Burn | Targets visceral fat stored around organs and muscles | 14% reduction in visceral fat in 16 weeks |
| Preserve | Helps retain lean mass during weight loss | Retains 98% of lean mass |
| Protect | Supports healthy muscle to restore active metabolism | Optimizes energy use and regulates body weight |
The Trilivy Reset Fueling line enhanced with MetaVantage Technology supports metabolic health by helping reduce waist circumference while supporting normal fat metabolism and healthy insulin function. The brand launch strengthens the connection between the brand and its nationwide network of independent coaches. Clinical research has shown individuals using the company’s coach-supported program lost up to 10x more weight and 17x more fat than those trying to lose weight on their own.
Newly formulated meal replacements, called Fuelings, are planned to debut in August. Medifast is a health and wellness company known for its science-backed comprehensive metabolic health system, designed to address the challenges of metabolic dysfunction through a holistic approach integrating plans, products, personal coaching, and behavioral science support.
How will the transition from OPTAVIA to Trilivy impact Medifast's existing customer base and brand loyalty?
What are the expected financial implications of this rebranding and product launch on Medifast's revenue and market share?
How will Medifast differentiate Trilivy from competitors in the crowded metabolic health and weight loss market?
























