BMS cuts BREYANZI monitoring proximity to 14 days
Bristol Myers Squibb Canada updated the product monograph for BREYANZI, reducing the required proximity to a specialized treatment centre from 28 days to 14 days. Driving restrictions were also lowered from eight weeks to four weeks. Clinical decisions remain with the treating healthcare professional.

*this image is generated using AI for illustrative purposes only.
Bristol Myers Squibb Canada (BMS) has updated the Canadian product monograph for BREYANZI® (lisocabtagene maraleucel), a CD19-directed chimeric antigen receptor T (CAR T) cell therapy. The update reduces the duration of certain post-treatment monitoring and activity restrictions for eligible patients following infusion.
The revised guidance lowers the recommended duration for patients to remain in close proximity to a specialized treatment centre from 28 days to 14 days following infusion. Additionally, driving restrictions have been reduced from eight weeks to four weeks.
Clinical decisions regarding patient discharge and ongoing monitoring will continue to be determined by the treating healthcare professional based on individual patient needs.
| Parameter | Previous Duration | Updated Duration |
|---|---|---|
| Proximity to specialized treatment centre | 28 days | 14 days |
| Driving restrictions | 8 weeks | 4 weeks |
Will similar monitoring updates be adopted by regulatory bodies in other markets for BREYANZI?
How might reduced proximity requirements impact the operational capacity and throughput of specialized treatment centers?
Could these changes improve patient access to CAR T therapies in regions located far from specialized facilities?
























