BioNTech's Breast Cancer Drug Breakthrough: Outperforms Roche's Kadcyla in Clinical Trial

1 min read     Updated on 05 Sept 2025, 03:54 PM
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Shriram ShekharScanX News Team
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Overview

BioNTech's experimental breast cancer drug showed promising results in a late-stage clinical trial, outperforming Roche's Kadcyla. The study, conducted with Duality Biotherapeutics, involved 228 advanced breast cancer patients in China. Patients treated with BioNTech's drug showed a reduced likelihood of cancer progression or death compared to those on Kadcyla. This marks BioNTech's first successful late-stage cancer trial, representing a significant step towards diversifying beyond COVID-19 vaccines and expanding into oncology.

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*this image is generated using AI for illustrative purposes only.

BioNTech SE, known for its COVID-19 vaccine success, has achieved a significant milestone in its cancer research efforts. The company's experimental breast cancer drug has shown promising results in a clinical trial, outperforming Roche's established therapy, Kadcyla.

Trial Success and Collaboration

The trial, conducted in collaboration with Chinese biotech firm Duality Biotherapeutics, marks BioNTech's first successful late-stage trial in cancer treatment. This achievement represents a crucial step towards potential regulatory approval for one of BioNTech's cancer compounds.

Trial Details and Results

The study involved 228 patients in China with advanced breast cancer, specifically those whose cancers had spread or were inoperable. These patients had previously undergone treatment with chemotherapy and trastuzumab. The results demonstrated that patients treated with BioNTech's new drug showed a reduced likelihood of cancer progression or death compared to those treated with Roche's Kadcyla.

Strategic Implications for BioNTech

This breakthrough is particularly significant for BioNTech as it seeks to diversify its portfolio beyond COVID-19 vaccine revenues. Cancer treatment represents a key growth area for the company, and this success could pave the way for expanded opportunities in oncology research and development.

Partner Success

Duality Biotherapeutics, BioNTech's partner in this endeavor, specializes in developing antibody-drug conjugates for cancer treatment. The success of this trial has had a positive impact on Duality's market performance, with its stock price surging over 280% since its listing on the Hong Kong stock exchange in April.

Looking Ahead

While this trial success is a significant step forward, further research and regulatory approvals will be necessary before the drug can be made available to patients. Nevertheless, this development represents a promising advance in breast cancer treatment and solidifies BioNTech's position as a key player in both vaccine technology and cancer therapeutics.

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